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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD2
All Species:
24.85
Human Site:
S646
Identified Species:
54.67
UniProt:
O14939
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14939
NP_002654.3
933
105987
S646
I
E
N
Q
F
F
I
S
C
S
D
G
R
T
V
Chimpanzee
Pan troglodytes
XP_511291
924
105027
S646
I
E
N
Q
F
F
I
S
C
S
D
G
R
T
V
Rhesus Macaque
Macaca mulatta
XP_001117754
892
101098
S605
I
E
N
Q
F
F
I
S
C
S
D
G
R
T
V
Dog
Lupus familis
XP_536610
854
96426
V588
K
D
Y
S
N
L
I
V
K
D
W
V
Q
L
D
Cat
Felis silvestris
Mouse
Mus musculus
P97813
933
106150
S646
I
E
N
Q
F
F
I
S
C
S
D
G
R
T
V
Rat
Rattus norvegicus
P70498
933
106019
S646
I
E
N
Q
F
F
I
S
C
S
D
G
R
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422793
1072
123414
F783
I
Y
I
E
N
Q
F
F
I
S
C
A
D
D
K
Frog
Xenopus laevis
NP_001129642
1039
119219
F749
I
Y
I
E
N
Q
F
F
I
S
C
A
D
N
K
Zebra Danio
Brachydanio rerio
XP_694649
927
106849
S639
L
E
N
Q
F
F
I
S
C
A
E
E
K
N
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001194932
825
94056
H559
F
T
N
I
V
I
S
H
R
Q
S
K
T
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M9W8
1046
118792
S739
I
E
N
Q
F
F
I
S
G
L
E
K
E
D
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
92.1
77.2
N.A.
90
89.5
N.A.
N.A.
48.8
50.9
59.2
N.A.
N.A.
N.A.
N.A.
36.2
Protein Similarity:
100
97.2
93.7
80.7
N.A.
93.8
93.1
N.A.
N.A.
63.3
66.2
73.5
N.A.
N.A.
N.A.
N.A.
53.1
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
13.3
13.3
60
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
N.A.
20
20
86.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.2
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
19
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
55
0
19
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
10
46
0
19
19
10
% D
% Glu:
0
64
0
19
0
0
0
0
0
0
19
10
10
0
0
% E
% Phe:
10
0
0
0
64
64
19
19
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
46
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
73
0
19
10
0
10
73
0
19
0
0
0
0
0
0
% I
% Lys:
10
0
0
0
0
0
0
0
10
0
0
19
10
0
19
% K
% Leu:
10
0
0
0
0
10
0
0
0
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
73
0
28
0
0
0
0
0
0
0
0
19
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
64
0
19
0
0
0
10
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
46
0
10
% R
% Ser:
0
0
0
10
0
0
10
64
0
64
10
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
10
46
10
% T
% Val:
0
0
0
0
10
0
0
10
0
0
0
10
0
0
55
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
19
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _